PUBLICATIONS

- Publications

- Patents

Journal papers

[Pubulications]

 

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​97) Kim, G. H., Jeon, H., Khobragade, T. P., Patil, M. D., Sung, S., Yoon, S., ... & Yun, H. (2019). Enzymatic synthesis of sitagliptin intermediate using a novel ω-transaminase. Enzyme and microbial technology120, 52-60.


​96) Patil, M. D., Grogan, G., Bommarius, A., & Yun, H. (2018). Oxidoreductase-catalyzed synthesis of chiral amines. ACS Catalysis8(12), 10985-11015.


​95) Patil, M. D., Grogan, G., & Yun, H. (2018). Biocatalyzed C− C Bond Formation for the Production of Alkaloids. ChemCatChem10(21), 4783-4804.


​94) Sung, S., Jeon, H., Sarak, S., Ahsan, M. M., Patil, M. D., Kroutil, W., ... & Yun, H. (2018). Parallel anti-sense two-step cascade for alcohol amination leading to ω-amino fatty acids and α, ω-diamines. Green chemistry20(20), 4591-4595.

​93) Jeon, H., Sarak, S., Lee, S. H., Bea, H. S., Patil, M., Kim, G. H., ... & Yun, H. (2018). Characterization of ELP-fused ω-Transaminase and Its Application for the Biosynthesis of β-Amino Acid. Biotechnology and bioprocess engineering23(5), 481-489.

 

​92) Ahsan, M., Patil, M., Jeon, H., Sung, S., Chung, T., & Yun, H. (2018). Biosynthesis of Nylon 12 Monomer, ω-Aminododecanoic Acid Using Artificial Self-Sufficient P450, AlkJ and ω-TA. Catalysts8(9), 400.

 

​91) Shin, Y. C., Yun, H., & Park, H. H. (2018). Structural dynamics of the transaminase active site revealed by the crystal structure of a co-factor free omega-transaminase from Vibrio fluvialis JS17. Scientific reports8(1), 11454.

​90) D Patil, M., Grogan, G., Bommarius, A., & Yun, H. (2018). Recent advances in ω-transaminase-mediated biocatalysis for the enantioselective synthesis of chiral amines. Catalysts8(7), 254.

 

89) Ahsan, M. M., Jeon, H., P. Nadarajan, S., Chung, T., Yoo, H. W., Kim, B. G., ... & Yun, H. (2018). Biosynthesis of the nylon 12 monomer, ω‐Aminododecanoic acid with novel CYP153A, AlkJ, and ω‐TA enzymes. Biotechnology journal13(4), 1700562.

 

88) Seo, J. H., Min, W. K., Lee, S. G., Yun, H., & Kim, B. G. (2018). To the Final Goal: Can We Predict and Suggest Mutations for Protein to Develop Desired Phenotype?. Biotechnology and bioprocess engineering23(2), 134-143.

87) Ahsan, M., Sung, S., Jeon, H., Patil, M., Chung, T., & Yun, H. (2017). Biosynthesis of medium-to long-chain α, ω-diols from free fatty acids using CYP153A monooxygenase, carboxylic acid reductase, and E. coli endogenous aldehyde reductases. Catalysts8(1), 4.


86) kannan Maruthamuthu, M., Selvamani, V., Nadarajan, S. P., Yun, H., Oh, Y. K., Eom, G. T., & Hong, S. H. (2018). Manganese and cobalt recovery by surface display of metal binding peptide on various loops of OmpC in Escherichia coli. Journal of industrial microbiology & biotechnology45(1), 31-41.

 

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85) Mathew S , Nadarajan SP , Sundaramoorthy U , Jeon H , Chung T , Yun H*  (2017.04) . Biotransformation of beta-keto nitriles to chiral (S)-beta-amino acids using nitrilase and omega-transaminase . DOI 10.1007/s10529-016-2271-4

 

84) Ravikumar Y , Nadarajan SP , Lee CS , Yun H* (2017 02). Engineering an FMN-based iLOV protein for the detection of arsenic ions. DOI:10.1016/j.ab.2017.02.012

 

83) Kanagavel Deepankumar, Nadarajan Saravanan Prabhu, June-Hyung Kim, Yun H*(2017.05). Protein engineering for covalent immobilization and enhanced stability through incorporation of multiple noncanonical amino acids. DOI 10.1007/s12257-017-0127-y

82) Prabhu NS , Yun H* (2017.06).Comparative analysis of polyspecificity of the endogenous tRNA synthetase of different expression host towards photocrosslinking amino acids using an in silico approach.DOI:10.1016/j.jmgm.2017.06.005

 

81) H yunwoo Jeon, Sanghan Yoon, Murshidul Ahsan, Sihyong Sung, Geon-Hee Kim, Uthayasuriya Sundaramoorthy, Seung-Keun Rhee, Yun H* (2017.08). The Kinetic Resolution of Racemic Amines Using a Whole-Cell Biocatalyst Co-Expressing Amine Dehydrogenase and NADH Oxidase. DOI: 10.3390/catal7090251

 

80) Saravanan Prabhu Nadarajan, Kanagavel Deepankumar, Joo-Hyun Seo, Yun H* (2017.08). Evaluating the role of puckering and fluorine atom in stability and folding of fluoroproline containing proteins.DOI 10.1007/s12257-017-0257-2

79) Md Murshidul Ahsan, Sihyong Sung, Hyunwoo Jeon, Mahesh D. Patil, Taeowan Chung and Yun H*(2017.12). Biosynthesis of Medium- to Long-Chain,!-Diols from Free Fatty Acids Using CYP153A Monooxygenase, Carboxylic Acid Reductase, and E. coli Endogenous Aldehyde Reductases.DOI:10.3390/catal8010004

 

78) Hong EY , Lee SG , Park BJ , Lee JM , Yun H* , Kim BG .(2017.09)Simultaneously Enhancing the Stability and Catalytic Activity of Multimeric Lysine Decarboxylase CadA by Engineering Interface Regions for Enzymatic Production of Cadaverine at High Concentration of Lysine. DOI:10.1002/biot.201700278  

 

 

 

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77) Mathew S, Deepankumar K, Shin G, Hong EY,  Kim B-G, Chung T, Yun H*. (2016, 07) Identification of novel thermostable ω-transaminase and its application for enzymatic synthesis of chiral amines at high temperature. RSC Adv., 2016, 6; 69257-60.

 

76) Durairaj P, Hur JS, Yun H*. (2016, 07) Versatile biocatalysis of fungal cytochrome P450 monooxygenases. Microb Cell Fact. 15(1):125. doi: 10.1186/s12934-016-0523-6.

 

75) Jung E, Park BG, Ahsan MM, Kim J, Yun H*, Choi KY, Kim BG. (2016, 06) Production of ω-hydroxy palmitic acid using CYP153A35 and comparison of cytochrome P450 electron transfer system in vivo. Appl Microbiol Biotechnol. On-line

 

74) Mathew S, Nadarajan SP, Chung T, Park HH, Yun H*. (2016, 06) Biochemical characterization of thermostable ω-transaminase from Sphaerobacter thermophilus and its application for producing aromatic β- and γ-amino acids. Enzyme Microb Technol. 87-88:52-60.

 

73) Ravikumar Y, Nadarajan SP, Lee CS, Jung S, Bae DH, Yun H*. (2016, 03) FMN-Based Fluorescent Proteins as Heavy Metal Sensors Against Mercury Ions. J Microbiol Biotechnol. 26(3):530-9.

 

72) Mathew S, Jeong SS, Chung T, Lee SH, Yun H*.(2016,01) Asymmetric synthesis of aromatic  β-amino acids using ω-transaminase: Optimizing the lipase concentration to obtain thermodynamically unstable β-keto acids.Biotechnol J. 11(1):185-90.

 

 

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71) Ravikumar Y, Nadarajan SP, Yoo TH, Lee CS, Yun H*. (2015,12) Incorporating unnatural amino acids to engineer biocatalysts for industrial bioprocess applications.Biotechnol J. 10(12):1862-76. (Invited review article)

 

70) Maruthamuthu MK, Nadarajan SP, Ganesh I, Ravikumar S, Yun H*, Yoo IK, Hong SH.(2015, 11) Construction of a high efficiency copper adsorption bacterial system via peptide display and its application on copper dye polluted wastewater.Bioprocess Biosyst Eng. 38(11):2077-84.

 

69) Ravikumar, Y., Nadarajan, S.P., Hyeon Yoo, T., Lee, C.-S., Yun H* (2015, 08) Unnatural amino acid mutagenesis-based enzyme engineering. Trends in Biotechnology 33(8): 462-470. (Invited review article)

 

68) Catherine, C., Oh, S.J., Lee, K.-H., (...), Yun, H., Kim, D.-M. (2015. 06) Engineering thermal properties of elastin-like polypeptides by incorporation of unnatural amino acids in a cell-free protein synthesis system. Biotechnology and Bioprocess Engineering 20(3): 417-422.

 

67) Durairaj, P., Malla, S., Nadarajan, S.P., (...), Kim, B.-G., Yun H* (2015. 04) Fungal cytochrome P450 monooxygenases of Fusarium oxysporum for the synthesis of ω-hydroxy fatty acids in engineered Saccharomyces cerevisiae. Microbial Cell Factories 14 (1), 45

 

66) Ravikumar, Y., Nadarajan, S.P., Lee, C.-S., Rhee, J.-K., Yun H* (2015.04) A New-Generation Fluorescent-Based Metal Sensor iLOV Protein. Journal of Microbiology and Biotechnology 25(4): 503-510.

 

65) Durairaj, P., Jung, E., Park, H.H., Kim, B.-G., Yun H* (2015.03) Comparative functional characterization of a novel benzoate hydroxylase cytochrome P450 of Fusarium oxysporum. Enzyme and Microbial Technology 70:58-65.

 

64) Shin, G., Mathew, S., Yun H* (2015.03) Kinetic resolution of amines by (R)-selective omega-transaminase from Mycobacterium vanbaalenii. Journal of Industrial and Engineering Chemistry 23:128-133.

 

63) EunOk JungAffiliated withSchool of Chemical and Biological Engineering, Seoul National University, Kwon-Young Choi, Da-hye Jung, Yun H*, Byung-Gee Kim (2015.03) Ortho-hydroxylation of mammalian lignan enterodiol by cytochrome P450s from Actinomycetes sp. Korean Journal of Chemical Engineering 32-3: 471- 47.

 

62) Mathew, S., Bea, H., Nadarajan, S.P., Chung, T., Yun H* (2015.02) Production of chiral β-amino acids using ω-transaminase from Burkholderia graminis. Journal of Biotechnology 196-197: 1-8.

 

61) Deepankumar, K., Nadarajan, S.P., Mathew, S., (...), Kim, B.-G., Yun H* (2015.02)  Engineering transaminase for stability enhancement and site-specific immobilization through multiple noncanonical amino acids incorporation. ChemCatChem 7(3): 417-421.

 

60) Deepankumar, K., Nadarajan, S.P., Bae, D.-H., (...), Choi, K.-Y., Yun H* (2015.02) Temperature sensing using red fluorescent protein. Biotechnology and Bioprocess Engineering 20(1): 67-72.

 

 

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59) Yang, B., Ayyadurai, N., Yun, H., (...), Zeng, H., Cha, H.J. (2014. 12) In vivo residue-specific dopa-incorporated engineered mussel bioglue with enhanced adhesion and water resistance. Angewandte Chemie - International Edition 53(49):13360-13364.

 

58) Nadarajan, S.P., Ravikumar, Y., Deepankumar, K., Lee, C.-S., Yun H* (2014. 11) Engineering lead-sensing GFP through rational designing. Chemical Communications 50(100):15979-15982.

 

57) Choi, K.-Y., Jung, E.O., Yun, H., Yang, Y.-H., Kim, B.-G. (2014.10) Engineering class I cytochrome P450 by gene fusion with NADPH-dependent reductase and S. avermitilis host development for daidzein biotransformation. Applied Microbiology and Biotechnology 98(19): 8191-8200.

 

56) Shon, M., Shanmugavel, R., Shin, G., (...), Lee, S.-H., Yun H* (2014.09) Enzymatic synthesis of chiral γ-amino acids using ω-transaminase. Chemical Communications 50 (84):12680-12683.

 

55) Nazir, K.H.M.N.H., Hassan, J., Durairaj, P., Yun, H. (2014.06) Isolation and identification of aspergillus flavus from poultry feed samples using combined traditional-molecular approach and expression of CYP64A1 at mRNA level. Pakistan Journal of Agricultural Sciences 51(2): 287-291.

 

54) Oh, S.-J., Lee, K.-H., Kim, H.-C., (...), Yun, H., Kim, D.-M. (2014.06) Translational incorporation of multiple unnatural amino acids in a cell-free protein synthesis system. Biotechnology and Bioprocess Engineering 19(3):426-432.

 

53) Deepankumar, K., Shon, M., Nadarajan, S.P., (...), Lee, S.-H., Yun H* (2014, 03) Enhancing thermostability and organic solvent tolerance of ω-transaminase through global incorporation of fluorotyrosine. Advanced Synthesis and Catalysis 356(5): 993-998.

 

 

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52) Deepankumar K, Nadarajan SP, Ayyadurai N, Yun H* (2013, 11) Enhancing the biophysical properties of mRFP1 through incorporation of fluoroproline. Biochem Biophys Res Commun. 440(4):509-14. 

 

51) Shin G, Mathew S, Shon M, Kim BG, Yun H*.(2013, 10) One-pot one-step deracemization of amines using ω-transaminases. Chem Commun. 49(77):8629-31.

 

50) Choi KY, Jung EO, Yun H*, Yang YH, Kazlauskas RJ, Kim BG* (2013, 07) Development of colorimetric HTS assay of cytochrome p450 for ortho-specific hydroxylation, and engineering of CYP102D1 with enhanced catalytic activity and regioselectivity. Chembiochem. 14(10):1231-8.

 

49) Sam Mathew, Giyoung Shin, Minsu Shon, and Yun H* (2013, 02) High Throughput Screening Methods for ω-Transaminases. Biotechnology and Bioprocess Engineering 18: 1-7

 

48) Jung DH, Choi W, Choi KY, Jung E, Yun H*, Kazlauskas RJ, Kim BG* (2013, 02) Bioconversion of p-coumaric acid to p-hydroxystyrene using phenolic acid decarboxylase from B. amyloliquefaciens in biphasic reaction system. Appl Microbiol Biotechnol. 97(4):1501-11. 

 

47) Nadarajan SP, Mathew S, Deepankumar K, Yun H* (2013, 02) An in silico approach to evaluate the polyspecificity of methionyl-tRNA synthetases. J Mol Graph Model. 39:79-86.

 

 

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46) Raghunathan G, Soundrarajan N, Sokalingam S, Yun H*, Lee SG. (2012, 12) Deletional protein engineering based on stable fold. PLoS One. 2012;7(12):e51510. doi: 10.1371/journal.pone.0051510

 

45) Niraikulam Ayyadurai, Kanagavel Deepankumar, Nadarajan Saravanan Prabhu, Nediljko Budisa, and Yun H** (2012, 08) Evaluation and biosynthetic incorporation of chlorotyrosine into recombinant proteins Biotechnology and Bioprocess Engineering 17: 679-686

 

44) Choi KY, Jung E, Jung DH, An BR, Pandey BP, Yun H*, Sung C, Park HY, Kim BG* (2-12.06) Engineering of daidzein 3'-hydroxylase P450 enzyme into catalytically self-sufficient cytochrome P450. Microb Cell Fact. 2012 11(1):81

 

43) Saravanan Prabhu N, Ayyadurai N, Deepankumar K, Chung T, Lim D, Yun H*. (2012, 06) Reassignment of sense codons: Designing and docking of proline analogs for Escherichia coli prolyl-tRNA synthetase to expand the genetic code. Journal of Molecular Catalysis B: Enzymatic 78:57-64

 

42) Mathew S and Yun H* (2012.06) ω-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids. ACS Catal. 2(6):9931001(invited review article)

 

41) Choi KY, Jung E, Jung DH, Pandey BP, Yun H*, Park HY, Kazlauskas RJ, Kim BG*(2012. 05) Cloning, expression and characterization of CYP102D1, a self-sufficient P450 m onooxygenase from Streptomyces avermitilis. FEBS J. 279(9):1650-62.

 

40) Seo YM, Mathew S, Bea HS, Khang YH, Lee SH, Kim BG, Yun H*. (2012, 03) Deracemization of unnatural amino acid: homoalanine using D-amino acid oxidase and ω-transaminase. Org Biomol Chem. 10(12):2482-5.

 

39) Seo Y, Kim A, Bea H, Lee S, Yun H*. (2012, 03) Asymmetric synthesis of l-6-hydroxynorleucine from 2-keto-6-hydroxyhexanoic acid using a branched-chain aminotransferase. Biocatalysis and Biotransformation 30(2) 171-176.

 

38) Choi KY, Jung EO, Jung DH, Pandey BP, Lee N, Yun H*, Park HY, Kim BG*. (2012.03) Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase. Biotechnol Bioeng. 109:630-6.

 

37) Nagasundarapandian Soundrarajan, Selvakumar Edwardraja, Sun-Gu Lee, Yun H*, Niraikulam Ayyadurai*. (2012.01) Enhancing the productivity of soluble green fluorescent protein through methionine-residue specific consensus approach. African Journal of Biotechnology 11(5):1059-1064

 

 

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36) Lee JH, Regmi SC, Kim JA, Cho MH, Yun H*, Lee CS, Lee J. * (2011.12) Apple flavonoid phloretin inhibits Escherichia coli O157:H7 biofilm formation and ameliorates colon inflammation in rats” Infect Immun. 79(12):4819-27.

 

35) Seo YM, Yun H*.* (2011,10) Enzymatic synthesis of L-tert-leucine with branched chain aminotransferase” J Microbiol Biotechnol. 21(10):1049-52.

 

34) Ayyadurai N, Prabhu NS, Deepankumar K, Kim A, Lee SG, Yun H*. (2011.09) Biosynthetic substitution of tyrosine in green fluorescent protein with its surrogate fluorotyrosine in Escherichia coli.Biotechnol Lett. 33(11):2201-7.

 

33) Ayyadurai N, Saravanan Prabhu N, Deepankumar K, Lee SG, Jeong HH, Lee CS, Yun H*. (2011.07) Development of a selective, sensitive, and reversible biosensor by the genetic incorporation of a metal-binding site into green fluorescent protein. Angew Chem Int Ed Engl. 50(29):6534-7.

 

32) Bea HS, Park HJ, Lee SH,* Yun H*. (2011.05) Kinetic resolution of aromatic β-amino acids by ω-transaminase. Chem. Commun. 47(20):5894-6.

 

31) Seo YM, Khang YH, Yun H*. (2011, 05). Kinetic resolution of 3-fluoroalanine using a fusion protein of d-amino Acid oxidase with vitroscilla hemoglobin. Biosci. Biotechnol. Biochem. 75(4):820-2.

 

30) Han-Seop Bea, Sang-Hyeup Lee, and Yun H*. (2011,04) “Asymmetric Synthesis of (R)-3-fluoroalanine from 3-fluoropyruvate Using Omega-transaminase” Biotechnology and Bioprocess Engineering 16: 291-296

 

29) Ayyadurai N, Prabhu NS, Deepankumar K, Jang YJ, Chitrapriya N, Song E, Lee N, Kim SK, Kim BG, Soundrarajan N, Lee S, Cha HJ, Budisa N, Yun H*. (2011, 04). Bioconjugation of l-3,4-dihydroxyphenylalanine containing protein with a polysaccharide. Bioconjug. Chem. 22(4):551-5.

 

28) Ayyadurai N, Deepankumar K, Prabhu NS, Lee S, Yun H*. (2011,03). A facile and efficient method for the incorporation of multiple unnatural amino acids into a single protein. Chem. Commun. 47(12):3430-2.

 

27) Kim B, Park OK, Bae JY, Jang TH, Yoon JH, Do KH, Kim BG, Yun H*, Park HH* (2011, 2) “Crystallization and preliminary X-ray crystallographic studies of β-transaminase from Mesorhizobium sp. strain LUK” Acta Crystallogr Sect F Struct Biol Cryst Commun. 67(2):231-3.

 

 

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26) Nagasundarapandian S, Merkel L, Budisa N, Govindan R, Ayyadurai N, Sriram S, Yun H*, Lee SG*. (2010, 12) “Engineering protein sequence composition for folding robustness renders efficient noncanonical amino acid incorporations” Chembiochem. 11(18):2521-4.

 

25) Ayyadurai Niraikulam , Yun H*yungdon and Lee Sun-Gu*(2010,10) “Role of Chaperon Co-Expression System in the Production of Recombinant Unnatural Proteins in Escherichia Coli” Research Journal of Biotechnology. 5(3):49-53.

24) Eun young Hong, Minho Cha, Yun H*, Byung-Gee Kim* (2010, 09) “Asymmetric synthesis of l-tert-leucine and l-3-hydroxyadamantylglycine using branched chain aminotransferase" Journal of Molecular Catalysis B: Enzymatic  66:228233.

 

23) Jang TH, Kim B, Park OK, Bae JY, Kim BG, Yun H*, Park HH*. (2010,08) “Crystallization and preliminary X-ray crystallographic studies of ω-transaminase from Vibrio fluvialis JS17” Acta Crystallogr Sect F Struct Biol Cryst Commun. 66( 8):923-5.

 

22) Han-Seop Bea, Young-Man Seo, Min-Ho Cha, Byung-Gee Kim and Yun H* (2010,06) “Kinetic resolution of α-methylbenzylamine by recombinant Pichia pastoris expressing ω-transaminase” Biotechnology and Bioprocess Engineering 15(3):429-434.

 

21) Bishnu Prasad Pandey, Changhyun Roh, Kwon-Young Choi, Nahum Lee, Eun Jung Kim, Sungghi Ko, Taejin Kim, Hyundon Yun  and Byung-Gee Kim* (2010,03) “Regioselective Hydroxylation of Daidzein Using P450 (CYP105D7) from Streptomyces avermitilis MA4680" Biotechnology &Bioengineering 105(4):697-704.

 

20) Ayyadurai Niraikulam*, Yun H*yungdon, Sakthivel Natarajan, (2010,02) “Protein coding genes for betterresolution of phylogenetic analysis”Research Journal of Biotechnology 5 (1):74

 

19) Ayyadurai Niraikulam*, Valarmathy Natarajan and Yun H*yungdon(2010, 02) “Effect of Indigofera Tinctoria Against Carbon Tetrachloride Induced Hepatic Damage in Albino Rats” Research Journal of Biotechnology 5 (1):5-8

 

 

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18) Ayyadurai Niraikulam, Yun H*yungdon and Lee Sungu* (2009,11)“Application of Expanding the Genetic Code”Research Journal of Biotechnology. 4(4):76-77

 

17) Niraikulam Ayyadurai, Rameshkumar Neelamegam, Soundrarajan Nagasundarapandian, Selvakumar Edwardraja, Hyung Soon Park, Soo Jae Lee, Tae Hyeon Yoo, Hyungdon Yoon and Sun-Gu Lee*. (2009,06) “Importance of expression system in the production of unnatural recombinant proteins in Escherichia coli” Biotechnology and Bioprocess Engineering14(3):257-265.

 

 

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16) Yun H* and Byung-Gee Kim (2008,11) "Asymmetric Synthesis of (S)-a-Methylbenxylamine by Recombinant Escherichia coli Co-Expressing Omega-transaminase and Acetolactate Synthase" Biosci. Biotechnol. Biochem., 72(11);3030-3.

 

15) Yun H* and Byung-Gee Kim (2008, 06) "Enzymatic Production of (R-Phenylacetylcarbinol by Pyruvate Decarboxylase from Zymomonas mobilis" Biotechnology and Bioprocess Engineering, 13:372-376.

 

14) June-Hyung Kim, Bum-Yeol Hwang, Jiwon Roh, Jong-Ki Lee, Kwang Kim, Sui-Lam Wong, Yun H*, Sun-Gu Lee and byung-Gee Kim* (2008, 06) Camparison of P-aprE, P-amyE, and P-P43 Promoter strength for beta-galactodidase and Staphylokinase Biotechnology and Bioprocess engineering, 13(3):313-318

 

 

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13) Minho Cha, Eun jung Kim, Yun H* and Byung-Gee Kim*. (2007,06) Synthesis of enanitopure (S)-2-hydroxyphenylbutanoic acid using novel hydroxy acid dehydrogenase from Enterobacter sp BK2K. Biotechnology Progress.23(3):606-12.

 

12) Juhan Kim, Dohyun Kyung, Yun H*, Byung-Kwan Cho, Joo-Hyun Seo, Minho Cha, and Byung-Gee Kim*. (2007, 03) Cloning and characterization of a novel β-transaminase from Mesorhizobium sp. strain LUK: A new biocatalyst for the synthesis of enantiomerically pure β-amino acids Applied and Environmental Microbiology. 73(6):1772-1782.

 

 

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11) Juhan Kim, Dohyun Kyung, Yun H*, Byung-Kwan Cho, and Byung-Gee Kim*. (2006, 11) Screening and Purification of a Novel Transaminase Catalyzing the Transamination of Aryl β-Amino Acid from Mesorhizobium sp. LUK. J. Microbiol. Biotechnol.  16(11):1832-1836.

 

10) Yun H*, Juhan Kim, Koteshwar Kinnera, and Byung-Gee Kim*. (2006, 02) Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and -transaminase. Biotechnology and Bioengineering. 93(2):391-395.

 

 

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9) Bum-Yeol Hwang, Byung-Kwan Cho, Yun H*, Kinera Koteshwar, and Byung-Gee Kim* (2005, 12) Revisit of aminotransferase in the genomic era and its application to biocatalysis. Journal of Molecular Catalysis B: Enzymatic. 37(1-6): 47-55.

 

8) Yun H*, Bum-Yeol Hwang, Jae-Hun Lee, and Byung-Gee Kim*. (2005, 08) Use of enrichment culture for directed evolution of the Vibrio fluvialis JS17 -transaminase, which is resistant to product inhibition by aliphatic ketones. Applied and Environmental Microbiology. 71(8): 4220-4224.

 

7) Yun H*, Hyeon-Lok Choi, Nitin W. Fadnavis and Byung-Gee Kim*. (2005, 04) Stereospecific synthesis of (R)-2-hydroxy carboxylic acids using recombinant E. coli BL21 overexpressing YiaE from Escherichia coli K12 and glucose dehydrogenase from Bacillus subtilis. Biotechnology Progress. 21(2):366-371.

 

 

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6) Yun H*, Byung-Kwan Cho, and Byung-Gee Kim*. (2004, 09) Kinetic resolution of sec-butylamine using omega-transaminase from Vibrio fluvialis JS17 under reduced pressure. Biotechnology and Bioengineering. 87(6): 772-778.

 

5) Yun H*, Seongyop Lim, Byung-Kwan Cho, and Byung-Gee Kim*. (2004, 04) -Amino acid:pyruvate transaminase from Alcaligenes denitrificans Y2k-2: a new catalyst for kinetic resolution of b-amino acids and amines. Applied and Environmental Microbiology.70(4): 2529-2534.

 

 

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4) Byung-Kwan Cho, Ho Jung Cho, Yun H* and Byung-Gee Kim*. (2003, 12) Simultaneous synthesis of enantiomerically pure (S)-amino acids and (R)-amines using a/w-aminotransferase coupling reactions with two-liquid phase reaction system. Journal of Molecular catalysis B: Enzymatic. 26 (3-6): 273-285.

 

3) Jong-Shik Shin, Yun H*, Jeong-Wook Jang, Insuk Park,and Byung-Gee Kim*. (2003, 06) Purification, characterization, and molecular cloning of a novel amine: pyruvate transaminase from Vibrio fluvialis JS17. Applied Microbiology and Biotechnology.61(5-6): 463-471.

 

2) Yun H*, Yung-Hun Yang, Byung-Kwan Cho, Bum-Yeol Hwang, Byung-Gee Kim*. (2003, 05) Simultaneous synthesis of enantiomerically pure (R)-1-phenylethanol and (R)--methylbenzylamine from racemic a-ethylbenzylamine using w-ransaminase/alcohol dehydrogenase/glucose dehydrogenase coupling reaction. Biotechnology Letters. 25(10): 809-814.

 

1) Byung-Kwan Cho, Ho Jung Cho, Sung-Hee Park, Yun H*, Byung-Gee Kim*. (2003, 03) Simultaneous synthesis of enantionerically pure (S)-amino acids and (R)-amines using coupled transaminase reactions. Biotechnology and Bioengineering.81(7): 783-789.